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Having been banned from undertaking any advertising, the major concern of the tobacco companies is that they are running out of promotion options

45, 46 A detailed analysis of the inflammatory infiltrates in a mouse model of chronic obstructive pulmonary disease (COPD) revealed that DC numbers in the airways raised gradually after a short period of continual smoking, reaching 10-fold levels after a chronic exposure for 6 months compared with the numbers in sham-exposed animals

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